THYROID HORMONES INFLUENCE ON PRIMARY HAEMOSTASIS STATUS AND CERTAIN ENZYME SYSTEMS IN LOCAL FORMS OF PERITONITIS

Abstract

One of the main significances in postoperative changes in biochemical and enzymes criterion of the pathology of the organs depends to T-3, the decreasing of level of which in blood plasma is related to disorders in peripheral T-4 monoiodising and depends on the level of the organisms intoxication. The influence of T-3 on the process of intraanginal blood coagulation is realizing on the level of the vessel component (synthesis of PGI2) primary haemostasis with following secondary increasing of functional antagonism in prostacycline-tromboxan system of regulation of the trombocytal-vessel haemostasis. The correction method for postoperative hypothyreosis, disorders in blood aggregation status regulation and polyorganic insufficiency syndrome was investigated. It¢s based on the enteral use of thyreoidine, itс efficacy is clinically proved in patients with local peritonitis.