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dc.contributor.authorChympoy, K.A.-
dc.contributor.authorPashkovska, N.V.-
dc.contributor.authorOlinyk, O.Ju.-
dc.contributor.authorTeleki, Ja.M.-
dc.date.accessioned2016-06-08T09:54:09Z-
dc.date.available2016-06-08T09:54:09Z-
dc.date.issued2015-
dc.identifier.urihttp://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/10994-
dc.description.abstractIn patients with chronic diffuse liver diseases there is a relation between the expression of Pro197Leu polymorphism of GPX1 gene and indices of cellular adhesion, which is revealed by a reliably higher content of soluble intercellular adhesion molecule-1 type in the blood serum in homozygotic carriers of Leu-allele. Changes of the endothelial functional state in patients with chronic diffuse liver diseases are associated with Pro197Leu polymorphism of GPX1 gene, which is proved by a reliably higher index of desquamated endotheliocytes amount and lower level of NO metabolites in the carriers of LeuLeu-genotype. Examination of the indices of cellular adhesion and functional endothelial state in patients with chronic diffuse liver diseases did not reveal their dependence on the distribution of A/C polymorphism of DIO1 gene.ru_RU
dc.language.isoenru_RU
dc.publisherInternational scientific-practical congress of pedagogues, psychologists and medics (5 th June, 2015, Geneva). – P. 231-238.ru_RU
dc.subjectchronic diffuse liver diseasesru_RU
dc.subjectхронические диффузные заболевания печениru_RU
dc.subjectхронічні дифузні захворювання печінкиru_RU
dc.subjectgene polymorphismru_RU
dc.subjectendotheliumru_RU
dc.subjectполиморфизм генаru_RU
dc.subjectэндотелийru_RU
dc.subjectполіморфізм генуru_RU
dc.subjectендотелійru_RU
dc.titleEffect of DIO1 and GPX1 gene polymorphism on the functional condition of the endothelium in patients with chronic diffuse liver diseaseru_RU
dc.typeArticleru_RU
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