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dc.contributor.authorVolosivska, Yuliia-
dc.contributor.authorHodovanets, Yuliia-
dc.contributor.authorYurieva, Lilia-
dc.date.accessioned2022-09-09T08:44:43Z-
dc.date.available2022-09-09T08:44:43Z-
dc.date.issued2020-
dc.identifier.citationСBU International Conference on Innovations in Science and Education 2020 (Medicine and Pharmacy), March 18-20, 2020, Pragueuk_UA
dc.identifier.other4. УДК 616.36-008.5/.6-053.1-071-074-
dc.identifier.otherDOI: doi.org/10.12955/pmp.v1.108-
dc.identifier.urihttp://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/20433-
dc.description.abstractIntroduction: The liver is the central organ of metabolic activity in the body. Objectives: The purpose of this study was to determine predictors, major clinical features, and laboratory criteria for the severity of disorders of the functional state of the hepatobiliary system in newborns with neonatal jaundice (NJ). The study included 164 full-term infants. The main group - 92 children, with manifestations of pathological jaundice, was divided into two subgroups, depending on the severity of the pathology, considering concomitant perinatal pathology. IA group (46 children) includes children, condition of which was defined as moderate, IB (46 children) – children, condition of which was defined as severe, the control group consisted of 72 healthy term infants. Conclusion: The results of the analysis of anamnestic and clinical-laboratory parameters in newborns with NJ showed on the background of a clinical signs of dysfunction of the hepatobiliary system, the presence of significant biochemical changes, especially enzymatic activity, including, ALT, AST, LDH, ALP, and γ-GT and, also an increase in TBS levels and an indirect bilirubin fraction, a decrease in total protein and albumin, glucose, a rise in urea, cholesterol and triglycerides. The use of a biochemical markers in newborns with clinical manifestations of neonatal jaundice, especially in cases of significant severity of the condition with concomitant perinatal pathology, requires more detailed analysis in order to determine the main pathogenesis of disorders of the functional state of the hepatobiliary system for the purpose of timely correction and improvement of the outcome of treatment.uk_UA
dc.language.isoenuk_UA
dc.publisherCBU International Conference Websiteuk_UA
dc.subjectnewbornuk_UA
dc.subjectjaundiceuk_UA
dc.subjectliveruk_UA
dc.subjecthepatobiliary systemuk_UA
dc.subjectbiochemical markersuk_UA
dc.titleSignificance of clinical and laboratory markers in disorders of the functional condition of the hepatobiliary system in neonatal jaundiceuk_UA
dc.typeArticleuk_UA
Appears in Collections:Статті. Кафедра акушерства, гінекології та перинатології



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