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Title: Effect of melatonin on the functioning of glutathione system in the liver of alloxan diabetic rats in lighting conditions around the clock
Authors: Яремій, Ірина Миколаївна
Кушнір, Олександра Юріївна
Харченко, Каріна Олександрівна
Keywords: melatonin
alloxan diabetes
glutathione system
Issue Date: 31-Jan-2016
Publisher: Science and Education a New Dimension. NATURAL AND TECHNICAL SCIENCE
Series/Report no.: IV (9), Issue: 83, P.71-74;
Abstract: Abstract. Insertion of melatonin for 7 days helped to reduce 1,7 times basal glucose level in the group of animals with overt diabetes. Activity of glucose-6-phosphate dehydrogenase, glutathione peroxidase and glutathione reductase in the liver of rats with overt diabetes was on 47%, 33%, and 35% respectively lower than in control rats that were under artificial equinox. In rat liver with overt and latent diabetes occurred reduction of reduced glutathione content on 25% and 41% respectively compared with those of control. Insertion of melatonin to diabetic rats helped in normalization of parameters.
ISSN: 2308 - 1996
Appears in Collections:Статті. Кафедра біоорганічної і біологічної хімії та клінічної біохімії

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